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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad23969104df1b70566d5d545e5c1f3708d5202b00317c6b794554810f8b2830' 
  AND token = 'HXj6cEbWS0eLoYHuOyM8VgwIXxplMIsNr+qePm0E9DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}