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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8339552a1d6d98a8fa9d537ea96bf8a5e3e169515785d710720a60a1430059e5' 
  AND token = 'z24X5QvlXww6zEDO6btEFhYW5Jxg7rCSW2oa9do46NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}