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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7349004e5b5bfb6993e014985b189ad5fb636c259d3929ab32d16a5efdf9c2f8' 
  AND token = 'GNKQJNc+WhkDP3ILrkl8kl0AK+nd3pja9q6QwSFd3ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}