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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f75c72bd07bd53aa4815e50789606306fc705e5ca75636192225001c6ace8d4' 
  AND token = 'Z0kBijcXd4S0Y8+XXEIgWGKY35NRZtm2fuWQ8C3NLUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}