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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1542e5324c48838b1b98a6775e198740837301ed9ecc982a15600fba1d389c1c' 
  AND token = 'rWVT7KCU0or9NH8i1WWXp2YYBKvPlLn5kXbsGDMHnz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}