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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fce675ce6d3addbb8f022dc8c7050cd25a6c1d1caf20b8fef75926ed2e4eb95' 
  AND token = 'r6tcOY2JPzLdYvHRZQnIfTawsxV6rwQEwTalBfG3Zr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}