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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e000e51ee26cfde42763198fb5d7aa6b40f7d54483e85f09659684991d8f0362' 
  AND token = 'GxQAAYffaWO7VJr3k2qMssJv6gOu0ZYupeum8y6Zw6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}