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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da00221f5e6401a1f67f83cd868f901590e83ee19a161b09c60440fc2d8e19a7' 
  AND token = 'UadNMUb4actn1sXMSo0M+vrsRNwoDiMfLOiOkxPGumM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}