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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f21b4ae87e7abc47ec945cdd640502abc5da441f271cf24b4becdf2f0cb4994' 
  AND token = 'FHYmwIRwF19vUU53oDnhNaAke/nJ8U9IHjm4H8rXSRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}