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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ff882ff88be91eb712f24d60bd1109a6d565b85b38f4ce830fd77403f854f0' 
  AND token = 'niKSvR5KKJ+s2Z3in7Ppqk3EX4sXXSHABJEsQbiv448=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}