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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46047eafdbdbfb8cca8a356efb453b8611fe05bc15bc28a24d572247fbc0bc6c' 
  AND token = 'jagTws1xFeFC1oX/mvuGWSux+Z66Z/td3p1tijSUhn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}