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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e0652937019b8de60c093e202f8d1dae7f583e245eb1e200da7e1536905bec4' 
  AND token = 'MZZIGf/1VE1g4aXsq8wbwkjpwG6jyQEfKjKO2FTSiv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}