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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599833305526e9768a66a9c87404c2b04afa68adea873017684ac97bd21c7614' 
  AND token = '2FjXH1ipJ2XtTgnl+QiTBLiAl35eI9jCs06UqxlTLYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}