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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5c24ec0dcb52a0e6a483b890079a9434b2621f072bb4db6124096567dac4a0c' 
  AND token = 'HGrByew5mvq3b5GzuFrooz6QY27NCToziYYLPs9DSp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}