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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e222bd5c6efb66b884c721d9ce7a357c67f43ed3f74cf5f5a4ccd3ebe7e3972' 
  AND token = 'CER+7L7iQZCyu5lkEObwWPd60mgbRMVSfI3S/6+WFXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}