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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '834945456a1e53dc88d75b75e4b89f5f1f8c927557d1dc8cf28a535bc45caa83' 
  AND token = 'PAfwbNDhYj6i4IAtdC5XqoV8TRsDUtuc1ayOgTJjHmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}