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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320db23ba5007d000c6e19dae4d59e4f3451fab18ee2a7cd2aece9720d170159' 
  AND token = 'rwNk3wIxLgGp+yAPAyWrgRHl7P7ghMW0CcX9/L7fU78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}