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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89ef3a9b168e535524a49bc75f9b15c0f3676ec1a2531c6ff33adb5fc509a399' 
  AND token = 'l7UgTM5M1MmJhr15RstoWxMvgQunNs+XTfKm6E37/Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}