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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2a3a6f02f0a007eb9c1bac92fc33085bdbe99b6dd78490ada4da5852d53e3b' 
  AND token = 'jJpJdJTzl3/oKgHeOGcZ7cNSSo7RILfS17MUTwJul14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}