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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53596bfac84924c047f4ba61178e7e57c2415dae1abeaf4910202e710ba0ad88' 
  AND token = 'eMK7ocpEwVzwrDDw+xXv6p1rYSrxdLJDQ12kwlVLkFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}