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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4d179d864f931cc9784ed1df4de931fab02ab8bec99da705e5089ad9912762' 
  AND token = '45PnVg8K7dJfbjFsWfssWIm930O2n2NxwMGbXP0eRj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}