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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1b84061f30dd873bb346ebc074fe1cdcf2efa2f3bb9e6950011410f4793240' 
  AND token = 'kh0HUhXDT7jPsALGy9qt88X1iAEX0Zo/Vs8cGIWX77s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}