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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93ff8369880f3701a00ec29825bf52258f2dd6f9f537b36c18169036e89d61c8' 
  AND token = 'Xspg3rEXQtTqoNqxkH9hqi+OccNhBBv3UcmZTeG2kf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}