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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea7bec4c775a10ee6fbd00689f503e9dc44f5b284960d36419a9358c2ac5817' 
  AND token = 'KK6v62YzwFVOY76oXF+MSNiXwTfji9wFd3UnQNd1GZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}