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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275218af98e0f9c17c0ceb08886909f197333148f3d4403ad592b9475784f9d3' 
  AND token = 'TPx8c2Qqw2CabkX6pwluf32gshOfLeaMpjMaXLfzjiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}