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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f154797dc8ed08d3ef4b38bd9ce63413300e968def568c687dff6e09663c3b' 
  AND token = '2J2cWDLYbyM3G5jk9ExX40yFCt6et2QGO+2xxajhTtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}