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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1258d6a95d37549994d1efc43ff998871d79c50fb85e127747e90b03b0dba061' 
  AND token = 'u3L1DL01CFc2fyHEU7jiUHKzKHij2bQS9MsMQ4KA0Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}