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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e41b5ed294ebfbaf3dcf541de08703f5106f5f5317be78036468a6f31d24dac1' 
  AND token = 'HVjO5CeYQJS3bCIuC/8FhZ1a09y6uGrLixgdSOMwEw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}