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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b4b1bdb8d8151f7a2a9bb011e0dd7940797b7096a6b1704c2fdb000941e298' 
  AND token = 'wIxyX4tz28+uCKqWyupLXz1Aa6QrfTRDIlBXsm28mEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}