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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b24ff47ccb959b3750d99fbb87d3764a2f29a6fd7d659ad0c9400539e65957f' 
  AND token = 'lXL2C9Pb1fk1WMKBM2LcHqa051nqBkZaoMtqfuKRzu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}