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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665fbcc2ae29a17e20b7a8d05f1c59e8082a851687a5428dd2ff924baa3b90e5' 
  AND token = 'NWuZDNC2Ehe6+H6C3QXFB/8nG0sPZ1oiVykkZbe2Lac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}