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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a755f6a5b0d4e0d9e95c419c227c7d7b84e9642539432a3b83d9d4b964a159cd' 
  AND token = 'uUVcQqrR8puZroBtwoySLHib9Z3JDWGvzf193xHl9C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}