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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cc1b2fe23998f92735b339f0e6570c33739bd4f782274b4a306288e39cf36f' 
  AND token = 'tyWGWL342yNmlWUpgdw79SipjpmKoExOddO03KVircw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}