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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8ee5950c890d56e442237612b5de51ee920034755ccaf5638496786a7c9c3c' 
  AND token = 'Yy8HxRJsAiBeW/QO9KJ0XXjLbwo7qD6Kcb2mjIDlIys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}