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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e020921d429b89f90e22e7eb909fb20f5b17bc1a908ba06b43e174d4637ad219' 
  AND token = 'Xs4QLqqTgjEMZbVcv8zyc7j6+u2oHTKc3G/EftNSt2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}