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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b8f048e41d88eb5dffb34de708397b583ded0d09ffe6dcf1c07cf1718c345d' 
  AND token = 'qU1g+VNHs1w2UkifnzD+qO7V+POg5HyjpsJwb0iI8GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}