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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494a4071c2290695ca1a20e0159fffb6b139e85d4ccf79f1e16f45f46928ae1b' 
  AND token = 'f3EJQu/u6I6cHZUnFMSlNSonMySMl5NBRPopVR+wQt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}