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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dd5fb1612651b3b43068dbb05b0ab5df887b91fd2de6dea4e436f29b34f7399' 
  AND token = 'EZsLpYWKb4qPc4uAKCwoU3f+D9tNGNRUxyOXnOVgp0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}