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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517eee9798185990e19fea3da1a861f6765fadbcecfc2695c4e83ba5de8a700c' 
  AND token = 'DIcakw4v7Sc8CT2AKYhbEKFAl0FcrEFxC0jSXR9VUys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}