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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9f349379b87546eb7ff7ebe40261a907016b6c46b9dce04cde53c61c49d83be' 
  AND token = 'W4cMg8Zvwqp3y+MZpz42nEZL4NECDM3o4m5UhM711HU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}