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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bfa12a43d50b1fbc587da2e5e54d8f65ca1afd960edbc7ce5df8185a954335' 
  AND token = 'BVqc73A6F1iJj66F6sMdpPALtcb5pNZq1DfaVMuxNJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}