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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fac4ed33ffe6a2d6039874c8e00f61515d0b334312fa12aa78ee575a9f8c13' 
  AND token = 'sXqLR4MX0GnVwcW1zV+V0+97AXJOJiXWIcOV92GN5BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}