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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bf6c5ca34f611078546a6f7d03e0de49352d32a8b727f240a93abcace4231e4' 
  AND token = 'lbJrU+lp2m2lO/FxFU09bsyHA06r65m8CBzhFfo5i7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}