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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ec90b6a62053b7fecefb0d7293225835f06898821361d01a06a4f0836b53b2' 
  AND token = 'sO/du4X8FrsroTRhxOxNQ04ybrfsHytr1PpSUOSeIQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}