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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c74b52887294f5037dfb4d89dfa27064ee7f64190d363354da70f83d68fcf5d' 
  AND token = 'S/r3vHV1fOC0wKcO1m5uIcrtWt9HCWBJ95uYmK2ClLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}