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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b1ed20e1e10a63e799069827f54c798d9a7e384b20373818c19793444cd878' 
  AND token = 'v2C4vkSdSLtdmuBeU930MWimaMTt/8xK1q8gzlDoufI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}