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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f62f7ed608149d489d09e6be280bf4d4174212ae695e2e0d78bac731650f222' 
  AND token = 'jznI8Uo5BIs3U4z2YkXkT4+G3y4vEOB5lfBbwfdA9GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}