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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41ca213f4e882d7070af5734742c41a72a18a9144d33cab37ac336d4e7b4707' 
  AND token = 'QoZNEb3lE4SDibTUiLWR9cCCwZUSXz2+8qqSB5oOcbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}