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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901df17227daab236fe845dcb3f4e2537e0b0bfbc6b1d0a3e797c6484272d9b3' 
  AND token = 'tZGdZRTMjPZuWzSallnmortQSvJLe1vs4Bes2caKLBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}