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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e95e4040543cecb5d295dc6247d6012f3dee4eca8b045af4217c218b9228e5' 
  AND token = '7j971NyrSGiKmArrsKMpVCzbwFDp2NcOFWUm1i6Lj7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}